Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

orcid logoMartin Čech avatar Martin Čechorcid logoLucille Delisle avatar Lucille Delisleorcid logoMo Heydarian avatar Mo Heydarianorcid logoYvan Le Bras avatar Yvan Le Brasorcid logoFlorian Heyl avatar Florian Heylorcid logoCristóbal Gallardo avatar Cristóbal GallardoGildas Le Corguillé avatar Gildas Le Corguilléorcid logoKhaled Jum'ah avatar Khaled Jum'ahFidel Ramirez avatar Fidel Ramirezorcid logoBjörn Grüning avatar Björn GrüningNiall Beard avatar Niall Beardorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoHans-Rudolf Hotz avatar Hans-Rudolf Hotzorcid logoTristan Reynolds avatar Tristan Reynoldsorcid logoMaria Doyle avatar Maria Doyleorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoPavankumar Videm avatar Pavankumar VidemWilliam Durand avatar William DurandVivek Bhardwaj avatar Vivek BhardwajFriederike Dündar avatar Friederike Dündarorcid logoAnup Kumar avatar Anup KumarMehmet Tekman avatar Mehmet Tekmanorcid logoHelena Rasche avatar Helena RascheVerena Moosmann avatar Verena Moosmannorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoBérénice Batut avatar Bérénice BatutMélanie Petera avatar Mélanie PeteraJoachim Wolff avatar Joachim Wolfforcid logoAnika Erxleben avatar Anika ErxlebenEkaterina Polkh avatar Ekaterina PolkhTorsten Houwaart avatar Torsten Houwaartorcid logoMallory Freeberg avatar Mallory FreebergLeily Rabbani avatar Leily Rabbaniorcid logoArmin Dadras avatar Armin DadrasDevon Ryan avatar Devon Ryanorcid logoSaskia Hiltemann avatar Saskia Hiltemann

Funding

These individuals or organisations provided funding support for the development of this resource

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ELIXIR Europe
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de.NBI
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Collaborative Research Centre 992
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Australian BioCommons
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The University of Melbourne
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Melbourne Bioinformatics
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UFR