Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

Mehmet Tekman avatar Mehmet Tekmanorcid logoMo Heydarian avatar Mo HeydarianFriederike Dündar avatar Friederike Dündarorcid logoBjörn Grüning avatar Björn Grüningorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoBérénice Batut avatar Bérénice Batutorcid logoMallory Freeberg avatar Mallory Freebergorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoKhaled Jum'ah avatar Khaled Jum'ahEkaterina Polkh avatar Ekaterina Polkhorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczNiall Beard avatar Niall Beardorcid logoHelena Rasche avatar Helena RascheMélanie Petera avatar Mélanie PeteraLeily Rabbani avatar Leily RabbaniTorsten Houwaart avatar Torsten HouwaartFidel Ramirez avatar Fidel Ramirezorcid logoYvan Le Bras avatar Yvan Le BrasJoachim Wolff avatar Joachim Wolfforcid logoNicola Soranzo avatar Nicola Soranzoorcid logoMaria Doyle avatar Maria Doyleorcid logoFlorian Heyl avatar Florian HeylDevon Ryan avatar Devon RyanVivek Bhardwaj avatar Vivek Bhardwajorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoLucille Delisle avatar Lucille DelisleAnup Kumar avatar Anup Kumarorcid logoSaskia Hiltemann avatar Saskia Hiltemann

Funding

These individuals or organisations provided funding support for the development of this resource

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CRC992
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ELIXIR Europe
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de.NBI
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UFR